Factors That Can Affect The Bioavailability Of CBD

CBD Bioavailability
CBD Bioavailability
CBD Bioavailability
CBD Bioavailability

CBD bioavailability is an important factor that can affect the benefits provided by this hemp-derived compound. It can be referred to as the amount of CBD entering your bloodstream. Increasing the bioavailability of CBD is important, as the health benefits you get from this compound can be dependent on it. Therefore, you have to be aware of different factors that can affect the bioavailability and increasing the delivery of CBD into your bloodstream.

There is a wide range of things that can affect the CBD bioavailability. Some of them are under your control, hence, you can bring them to your advantage. For those factors that are not under your control, you can maximize the effectiveness by selecting the right delivery method and the best CBD dosage. Hence, it can help you to increase the bioavailability, thereby increasing the effectiveness.

Factors That Can Affect The CBD Bioavailability

The following are some of the important factors that can affect the bioavailability of CBD:

Liver Function

The liver plays a great role in screening the compounds entering your blood and eliminating them from your body. Therefore, it is responsible for regulating the amount of CBD entering your bloodstream and removing it from the body after a while.

It is found that an impaired liver function can have a great impact on the effectiveness provided by CBD and how long it remains in your body. Studies suggest that people who have liver impairment had higher concentrations of CBD in the bloodstream and they also have long clearance times than normal people with a healthy liver.

It implies that the CBD bioavailability will be more in people with liver impairment and it will stay in the circulation for longer periods. So they will experience more effectiveness from CBD than normal people.

Other Health Conditions

Some other health conditions can also have a great impact on the absorption of CBD by your body. For example, when given CBD for people with Huntington’s disease (a progressive brain disorder), it is found that the absorption of CBD is very low than the normal people. Hence, such health conditions may reduce CBD bioavailability.


Taking CBD in higher doses can also increase the absorption of this compound. However, there is a peak level where the absorption will be maximum and it will not increase any more even if you increase the dosage beyond this peak level.

Other Foods

It is established that CBD will be absorbed maximum when it is taken with other foods, especially fatty foods. Hence, if you want to increase the bioavailability, it is better to take this compound on a full stomach than an empty stomach.